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| Caption | Schematic of gene targeting at the ROSA26 locus to generate the Gt(ROSA)26Sortm2(EIF1AX-bglA*)Dwi (R26(SYNbglA)R) allele. Shown are: the ROSA26 locus (top); the targeting construct containing the loxP-PGKneo-loxP SYNbglA cassette (mid), arrows represent loxP sites; the targeted locus (bottom). Targeted clones were confirmed by Southern blotting of EcoR1 digested genomic DNA with the probe shown to generate 15 kb and 8.4 kb bands from the wild type and targeted alleles, respectively. | ||||
| Copyright | This image is from McCutcheon SC, BMC Biol 2010;8():89, an open-access article, licensee BioMed Central Ltd. J:196052 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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