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| Caption | Generation of Braftm2Urr (BRafnfl), Braftm2.1Urr (BRaffl), and Braftm2.2Urr (BRafdel) alleles. In the conditional Braf allele, Braftm2Urr, exon 3 encoding part of the Ras-binding domain is flanked by loxP sites (arrowheads). Deletion of the neomycin resistance gene in the Brafnfl mice generated the Braftm2.1Urr (BRaffl) allele. Deletion of both exon 3 and the neomycin resistance gene generated the Braftm2.2Urr (BRrafdel) allele. Positions of primers used in PCR reactions to distinguish the different alleles are shown. | ||||||||
| Copyright | This image is from Pfeiffer V, PLoS One 2013;8(3):e58259, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199842 | ||||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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