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| Caption | Targeted modification of the Rheb gene. A, schematic structures of genomic Rheb sequences, the targeting construct, the targeted allele, the floxed allele (Rhebtm1.1Otsu), and the deleted allele that results when the floxed region is removed (from top to bottom). The black and white arrowheads represent loxP and flippase recognition target sites, respectively. The targeting construct includes the PGK-neo cassette flanked by flippase recognition target sites and a diphtheria toxin gene (DTA). The arrows correspond to the primer sequences for PCR screening. | ||||||
| Copyright | This image is from Tamai T, J Biol Chem 2013 Apr 5;288(14):10176-87 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:197831 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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