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| Caption | To generate the Pkn1tm1Kik allele, the targeting vector used to disrupt the Pkn1 gene was introduced into ES cells using conventional methods. (A) Schematic of the wild-type Pkn1-targeting construct and mutated allele. Exons are depicted by filled boxes. Restriction sites: H, HindIII; Xb, XbaI; X, XhoI; B, BamHI; S, SalI; E, EcoRI. Neor, neomycin resistance gene cassette. MC1-tk, MC1 promoter-driven thymidine kinase gene. | ||||
| Copyright | This image is from Yasui T, Proc Natl Acad Sci U S A 2012 Dec 18;109(51):21022-7. Copyright 2012 National Academy of Sciences, U.S.A. J:193187 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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