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Caption Zinc finger nuclease pair 204/205 promotes ROSA26 targeting by homologous recombination in mouse zygotes. (A) Homologous recombination targeting strategy for the insertion of the targeting vector gtR26_EGFP carrying EGFP driven by a CAG promoter into the ROSA26 locus, to generate Gt(ROSA)26Sorem1(CAG-EGFP)Ltku.
Copyright This image is from Hermann M, PLoS One 2012;7(9):e41796, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:191768
Associated
Alleles
Symbol Name
Gt(ROSA)26Sorem1(CAG-EGFP)Ltku gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Pawel Pelczar

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory