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| Caption | Generation of the Atmtm1Shzh and Atmtm1.1Shzh alleles. (B) The schematic diagram represents the murine Atm locus (top), targeting vector (second row), targeted allele, Atmtm1Shzh (AtmKDN, third row), and the neomycin (neo)-deleted mutant allele, Atmtm1.1Shzh (AtmKD, bottom). The 5' probe is marked as a black line. The exons and loxP sites are shown as solid boxes and open triangles, respectively. The exon containing the KD mutation is marked as an open box. Restriction site designations are as follows: X, XhoI; RV, EcoRV; H, HindIII. The map is not drawn to scale. | ||||||
| Copyright | This image is from Yamamoto K, J Cell Biol 2012 Aug 6;198(3):305-13, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:191288 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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