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Molecular Image Detail
Image
Caption Generation of the Kittm4.1Bsm allele. (A) Targeting strategy for the simultaneous knock-in of V558delta (exon 11) and T669I (exon 14) into the 129S1/Sv Kit locus. Blue and red bars denote the exons with the respective point mutations. Triangles (not drawn to scale) indicate loxP sites; white gaps indicate BamHI restriction sites; bar indicates 518-bp Southern blot probe. DTA, diphtheria toxin A gene; NEO, neomycin resistance gene.
Copyright This image is from Bosbach B, Proc Natl Acad Sci U S A 2012 Aug 21;109(34):E2276-83. Copyright 2012 National Academy of Sciences, U.S.A. J:188434
Associated
Alleles
Symbol Name
Kittm4.1Bsm KIT proto-oncogene receptor tyrosine kinase; targeted mutation 4.1, Peter Besmer

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory