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Image
Caption Gene-targeting strategy. (B) Schematic representation of the targeting vector, homologous recombinant allele (Vegfr3neoEGFPluc), and Flpe-mediated recombination to eliminate the selection cassette (PGK-neo) flanked by frt sites (black triangles), generating the Flt4tm1.1Sgo (Vegfr3EGFPluc) allele. The IRES-EGFPLuc cassette is integrated 149-nt downstream of the TGA stop codon.
Copyright This image is from Martinez-Corral I, Proc Natl Acad Sci U S A 2012 Apr 17;109(16):6223-8. Copyright 2012 National Academy of Sciences, U.S.A. J:183610
Associated
Alleles
Symbol Name
Flt4tm1.1Sgo FMS-like tyrosine kinase 4; targeted mutation 1.1, Sagrario Ortega

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory