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Caption (B) Scheme of the targeting strategy for Sulf2 to generate the Sulf2tm1Mmas allele. A stop-IRES-lacZ-polyA-pgk-Neo cassette was inserted into exon 5 of the Sulf2 gene. DTA, diphtheria toxin A fragment; E, EcoRI; K, KpnI; (K), a polymorphic KpnI site present in the 129 (targeted) allele but not in the C57BL/6 (wild-type) allele.
Copyright This image is from Nagamine S, J Biol Chem 2012 Mar 16;287(12):9579-90 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:183277
Associated
Alleles
Symbol Name
Sulf2tm1Mmas sulfatase 2; targeted mutation 1, Masayuki Masu

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory