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Molecular Image Detail
Image
Caption (A) Schematic representation of the ROSA26 Lox-STOP-Lox Bmi1 (Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki; Bmi1LSL) allele. Mice bearing the Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki allele can be mated to mice expressing Cre-recombinase to overexpress Bmi1 in a tissue specific manner, such as with the Tg(Pbsn-cre)4Prb transgenic mice to get Bmi1 expression in the prostate epithelium.
Copyright This image is from Nacerddine K, J Clin Invest 2012 May 1;122(5):1920-32 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184533
Associated
Alleles
Symbol Name
Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki gene trap ROSA 26, Philippe Soriano; targeted mutation 1, The Netherlands Cancer Institute

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory