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| Caption | Strategy for homologous recombination of Ad4gnt gene. (A) Wild-type Ad4gnt allele (top), targeting vector containing neomycin-resistance (PGK-gb2-neo) and diphtheria toxin A (DT-A) cassettes (middle), and predicted mutant allele, A4gnttm1Jnaka, generated by homologous recombination (bottom) are show. A4gnt inactivation was achieved by replacing genomic DNA sequences harboring exons 2 (E2) and 3 (E3), which correspond to the entire A4gnt coding region, with the neomycin-resistance gene. | ||||
| Copyright | This image is from Karasawa F, J Clin Invest 2012 Mar 1;122(3):923-34 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184485 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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