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Image
Caption (A) Homologous recombination of the targeting construct (Top) with the wild-type Lgals12 allele (Middle) results in the replacement of ~6 kb of Lgals12 DNA, encompassing exon III through IX, with a neomycin resistance cassette (pGK-neo) (Bottom). Corresponding homologous sequences in the targeting construct and the Lgals12 gene are depicted in blue (short arm) and red (long arm), respectively.
Copyright This image is from Yang RY, Proc Natl Acad Sci U S A 2011 Nov 15;108(46):18696-701. Copyright 2011 National Academy of Sciences, U.S.A. J:180097
Associated
Alleles
Symbol Name
Lgals12tm1Ftl lectin, galactose binding, soluble 12; targeted mutation 1, Fu-Tong Liu

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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory