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Caption (G) Il17f gene-targeting strategy for the generation of the Il17ftm1Awai allele. A reporter gene/resistance cassette (lacZ gene and a Ub1-Em7 promoter driven neomycin resistance gene, neo, flanked by loxP sites) was introduced into Il17f exon 2 and 3 of a BAC containing the IL17F gene locus. Embryonic stem cells were targeted with a BAC carrying the replaced Il17f gene locus and were subsequently screened. "a" and "b" represent amplicons for the wild-type and targeted allele respectively.
Copyright This image is from Haak S, J Clin Invest 2009 Jan;119(1):61-9 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:144710
Associated
Alleles
Symbol Name
Il17ftm1Awai interleukin 17F; targeted mutation 1, Ari Waisman

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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory