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Molecular Image Detail
Image
Caption (A) Schematic representation of the Col1a1tm1(CAG-Sirt2)Jmi (SIRT2STOP) transgenic construct that was targeted to the 3'-UTR of the collagen A1 locus of mouse embryonic stem cells by FLP recombination. Crossing to a transgene expressing Cre recombinase results in the removal of the floxed STOP sequence and expression of SIRT2.
Copyright This image is from Beirowski B, Proc Natl Acad Sci U S A 2011 Oct 25;108(43):E952-61. Copyright 2011 National Academy of Sciences, U.S.A. J:177468
Associated
Alleles
Symbol Name
Col1a1tm1(CAG-Sirt2)Jmi collagen, type I, alpha 1; targeted mutation 1, Jeffrey Milbrandt

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory