Gene Expression Image Detail

Reference

Figure

ID

J:309724 Rux D, et al., Dev Biol. 2021 Sep;477:49-63

3

MGI:7378139

Image

Caption

(A-H) Hoxa11eGFP staining in newborn wrists and ankles. Synovial lining (white arrows). Higher magnification images of boxed regions in A and B shown with (C-D) or without (E-F) DIC imaging reveal details of cell/tissue morphology. (G-H) RNAscope in newborn wrist and ankle. (I-L) Hoxa11eGFP staining in adult (2 months old) wrist (I) and ankle (J) joints. Synovial lining (I-J, white arrows) and fat pad of the ankle (J, asterisk). Higher magnification images (M-L) of boxed regions in I and J show Hoxa11eGFP with (M-N) and without (K-L) DIC imaging. Bone marrow stromal cells (I and J, red arrow heads). Dashed lines denote boundaries of cartilage zones. ossification centers (oc); articular cartilage (ac); epiphyseal cartilage (ec); calcified cartilage (cc); subchondral bone (sb). ha; hamate; cap, capitate; tm, tidemark; tr, trapezoid; lu, lunate; sc, scaphoid; ta, talus; ca, calcaneous. scale bar = 100 um.

Copyright

Reprinted with permission from Elsevier from 10.1016/j.ydbio.2021.05.007 Dev Biol 477: 49-63, Rux D; Helbig K; Koyama E; Pacifici M, Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice. Copyright 2021.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:7378475 (Hoxa11)
B	MGI:7378475 (Hoxa11)
C	MGI:7378475 (Hoxa11)
D	MGI:7378475 (Hoxa11)
E	MGI:7378475 (Hoxa11)
F	MGI:7378475 (Hoxa11)
G	MGI:7378534 (Hoxa11)
H	MGI:7378534 (Hoxa11)
I	MGI:7378475 (Hoxa11)
J	MGI:7378475 (Hoxa11)
K	MGI:7378475 (Hoxa11)
L	MGI:7378475 (Hoxa11)
M	MGI:7378475 (Hoxa11)
N	MGI:7378475 (Hoxa11)