Gene Expression Image Detail

Reference

Figure

ID

J:309724 Rux D, et al., Dev Biol. 2021 Sep;477:49-63

1

MGI:7378137

Image

Caption

(A-D) Whole mount imaging of Hoxa11eGFP embryos at E13.5, E14.5, E15.5, and E17.5. Orange arrows indicate distal zeugopod; blue arrows indicate knee. (E-L) Tissue sections of Hoxa11eGFP embryos at E13.5, (E,F). Orange arrows indicate wrist/ankle; blue arrows indicate elbow/knee. (G,H) E14.5 forelimb and hindlimb. (I-L) High magnification images from boxed areas in G and H - scaphoid (sc), lunate (lu) of the wrist (I); talus (ta), calcaneous (ca) of the ankle (K); knee (L); elbow (J). (M-R) Tissue sections at E15.5 of the entire limb zeugopod - wrist (M); ankle and knee (N); elbow (M, blue arrow indicates staining); overlap with Gdf5Cre;tdTomato (Gdf5CreTom) joint progenitors (yellow). (O-R) High magnification images of boxed regions in M and N - scaphoid (sc), lunate (lu) in the wrist (O); talus (ta), calcaneous (ca) in the ankle (P); knee (Q); elbow (R). (S-V) RNAscope in situ hybridization - wrist (S); elbow (T); ankle (U); knee (V). r, radius; u, ulna; h, humerus; t, tibia; f, femur. scale bar, 100 um.

Copyright

Reprinted with permission from Elsevier from 10.1016/j.ydbio.2021.05.007 Dev Biol 477: 49-63, Rux D; Helbig K; Koyama E; Pacifici M, Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice. Copyright 2021.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:7378475 (Hoxa11)
B	MGI:7378475 (Hoxa11)
C	MGI:7378475 (Hoxa11)
D	MGI:7378475 (Hoxa11)
E	MGI:7378475 (Hoxa11)
F	MGI:7378475 (Hoxa11)
G	MGI:7378475 (Hoxa11)
H	MGI:7378475 (Hoxa11)
I	MGI:7378475 (Hoxa11)
J	MGI:7378475 (Hoxa11)
K	MGI:7378475 (Hoxa11)
L	MGI:7378475 (Hoxa11)
M	MGI:7378475 (Hoxa11)
N	MGI:7378475 (Hoxa11)
O Hoxa11eGFP	MGI:7378475 (Hoxa11)
O merge	MGI:7378475 (Hoxa11)
S	MGI:7378534 (Hoxa11)
P Hoxa11egfp	MGI:7378475 (Hoxa11)
P merge	MGI:7378475 (Hoxa11)
U	MGI:7378534 (Hoxa11)
R Hoxa11egfp	MGI:7378475 (Hoxa11)
R merge	MGI:7378475 (Hoxa11)
T	MGI:7378534 (Hoxa11)
Q Hoxa11egfp	MGI:7378475 (Hoxa11)
Q merge	MGI:7378475 (Hoxa11)
V	MGI:7378534 (Hoxa11)