Phenotype Image Detail

Image

Caption

Mkx^tm1Miu/Mkx^tm1Miu (-/-) mice show reduced tendon formation. (a) A kinky tail with an incomplete penetrance in the null mice. An upper mutant homozygous mouse presents a kinky tail, and a lower sibling heterozygous mouse does not. (b-i) Tendons of null mice show reduced differentiation compared with those of littermate wild-type (WT). Tendons of erector spinae muscles (b, c), forelimb (d, e), and dorsal sacrococcygeal muscles (f-i) were hypoplastic. (h) and (i) are higher magnification of (f) and (g), respectively.

Copyright

This image is from Kimura W, Genesis 2011 Jan;49(1):2-9, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:167977

Associated Alleles

Symbol	Name
Mkx^tm1Miu	mohawk homeobox; targeted mutation 1, Naoyuki Miura

Associated Genotypes

Allelic Composition	Genetic Background
Mkx^tm1Miu/Mkx^tm1Miu	involves: 129 * C57BL/6