Phenotype Image Detail

Image

Caption

Increased number of clathrin-coated vesicles (CCVs)/cages at synapses of neuronal cultures from an Dnajc6^tm1Legr/Dnajc6^tm1Legr (Auxilin KO) mouse as revealed by electron microscopy. Representative wild-type (control) and knockout synapses are shown. At right is a quantification of the percentage of CCVs/cages (coated structures; CSs) relative to synaptic vesicles (SVs) in the two genotypes. (Scale bars, 200 nm.)

Copyright

This image is from Yim YI, Proc Natl Acad Sci U S A 2010 Mar 2;107(9):4412-7. Copyright 2010 National Academy of Sciences, U.S.A. J:158574

Associated Alleles

Symbol	Name
Dnajc6^tm1Legr	DnaJ heat shock protein family (Hsp40) member C6; targeted mutation 1, Lois Greene

Associated Genotypes

Allelic Composition	Genetic Background
Dnajc6^tm1Legr/Dnajc6^tm1Legr	B6.129-Dnajc6^tm1Legr