Phenotype Image Detail

Image

Caption

Acrosome and manchette defects in Lrguk^Kaos/Lrguk^Kaos (Kaos/Kaos) mice. (A) PAS stained testis sections from wild-type (WT/WT) and mutant mice. Arrows indicate mis-localised proacrosomal vesicles. (B) Transmission electron microscopy of elongated spermatid from WT and mutant mice. The green arrow indicates a detached acrosome. Nu = nucleus. Scale bar = 2 um. (C) Transmission electron microscopy showing abnormal manchette structure including a constricted perinuclear ring (green arrow). Red arrows indicate microtubules within the manchette.

Copyright

This image is from Liu Y, PLoS Genet 2015 Mar;11(3):e1005090, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:222840

Associated Alleles

Symbol	Name
Lrguk^Kaos	leucine-rich repeats and guanylate kinase domain containing; kaos

Associated Genotypes

Allelic Composition	Genetic Background
Lrguk^Kaos/Lrguk^Kaos	involves: C57BL/6 * CBA