Phenotype Image Detail

Image

Caption

Gross appearance of spleens of wild-type (WT) and Lrrc8a^tm1.1Geha/Lrrc8a^tm1.1Geha (Lrrc8a-/-) mice and H&E staining (bars, 200 um). Mutant mice have small spleens with well-preserved architecture.

Copyright

This image is from Kumar L, J Exp Med 2014 May 5;211(5):929-42, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:211308

Associated Alleles

Symbol	Name
Lrrc8a^tm1.1Geha	leucine rich repeat containing 8A VRAC subunit A; targeted mutation 1.1, Raif S Geha

Associated Genotypes

Allelic Composition	Genetic Background
Lrrc8a^tm1.1Geha/Lrrc8a^tm1.1Geha	B6.129S1(Cg)-Lrrc8a^tm1.1Geha