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Phenotype Image Detail
Image
Caption Bright and fluorescent images of PECAM-1 immunostained E9.5-10.5 (a) wild-type and (b) pac/pac (pacman) embryos. Arrowheads and arrows indicate perturbed pharyngeal arch artery formation and anomalies in vascular plexus development, respectively. The pharyngeal arch arteries are variable in size and mutants exhibit dilated rostral arch arteries. Mutant embryos exhibit a reduction in microvasculature.
Copyright This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522
Associated
Alleles
Symbol Name
pac pacman
Associated
Genotypes
Allelic Composition Genetic Background
pac/pac involves: 129S1/Sv * C57BL/6 * FVB/NJ

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory