Phenotype Image Detail

Image

Caption

Early innervation defects in Srrm4^{tm1b(EUCOMM)Wtsi}/Srrm4^{tm1b(EUCOMM)Wtsi} (delta7-8/delta7-8) mice. A. Whole E10.5 and (B) E12.5 embryos were stained with an antibody to neurofilament. Two embryos of each genotype and at each time point are shown. Arrows highlight innervation defects. Insets show higher magnification of boxed regions "a" and "b" in each panel. I: trigeminal nerves; II: hypoglossal nerves; III: spinal nerves.

Copyright

This image is from Quesnel-Vallieres M, Genes Dev 2015 Apr 1;29(7):746-59, and is displayed with the permission of Cold Spring Harbor Laboratory Press, who owns the Copyright. J:221584

Associated Alleles

Symbol	Name
Srrm4^tm1b(EUCOMM)Wtsi	serine/arginine repetitive matrix 4; targeted mutation 1b, Wellcome Trust Sanger Institute

Associated Genotypes

Allelic Composition	Genetic Background
Srrm4^tm1b(EUCOMM)Wtsi/Srrm4^tm1b(EUCOMM)Wtsi	involves: C57BL/6J * C57BL/6N