Phenotype Image Detail

Image

Caption

(A) Severe perivascular fibrosis in Raf1^tm1.1Bgn/Raf1⁺ heart after transverse aortic constriction (TAC) (Picrosirius red (PSR) staining; original magnification, 200X). (B) Gross appearance of a mutant heart (left) with a severe infarct after TAC, and severe fibrosis (right) in the infarcted region (PSR staining; original magnification, 100X).

Copyright

This image is from Wu X, J Clin Invest 2011 Mar 1;121(3):1009-25 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172034

Associated Alleles

Symbol	Name
Raf1^tm1.1Bgn	v-raf-leukemia viral oncogene 1; targeted mutation 1.1, Benjamin G Neel

Associated Genotypes

Allelic Composition	Genetic Background
Raf1^tm1.1Bgn/Raf1^+	involves: 129S6/SvEvTac * C57BL/6NCr