Phenotype Image Detail

Image

Caption

c, Nine-month-old Gnptab^nym/Gnptab^nym (nym) and wild-type (+/+) brain sections were stained with filipin for the detection of cholesterol. The molecular layer of the mutant cerebellum showed increased storage in comparison with the wild-type control. Scale bar, 50 um. D, Nine-month-old mutant and wild-type brain sections were stained with periodic acid-Schiff for detection of glycolipids. Increased storage was detected in the cerebellum (top, specifically in the molecular layer), the cortex (middle, specifically in layers 3-5), and the hippocampus (bottom, specifically in layers CA1 and CA3). Scale bar, 50 um.

Copyright

This image is from Paton L, J Biol Chem 2014 Sep 26;289(39):26709-21 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:218156

Associated Alleles

Symbol	Name
Gnptab^nym	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits; Nymphe

Associated Genotypes

Allelic Composition	Genetic Background
Gnptab^nym/Gnptab^nym	involves: BALB/cAnNHsd * C3H/HeNHsd