Phenotype Image Detail

Image

Caption

Hematoxylin and eosin stained sections of caput (E, F) and cauda (G, H) epididymides of wild-type (+/+) and Baz1a^tm1.1Sky/Baz1a^tm1.1Sky (-/-) mice. Caput epididymides were devoid of sperm in the mutant in contrast to wild-type, which displayed lumens packed with mature sperm (E,F). Unlike wild-type cauda epididymides, where darkly stained sperm heads and tangles of lightly stained tails were visble (G), those from the mutant contained only debris and degenerating, mostly round cells that likely sloughed from the seminiferous tubules (H). Bar = 20 um.

Copyright

This image is from Dowdle JA, PLoS Genet 2013 Nov;9(11):e1003945, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:223044

Associated Alleles

Symbol	Name
Baz1a^tm1.1Sky	bromodomain adjacent to zinc finger domain 1A; targeted mutation 1.1, Scott Keeney

Associated Genotypes

Allelic Composition	Genetic Background
Baz1a^tm1.1Sky/Baz1a^tm1.1Sky	involves: C57BL/6J * FVB/NJ