Phenotype Image Detail

Image

Caption

(B) Scanning electron microscopy shows scattered loss of outer hair cells (arrows) in the basal turn and dysmorphology of the stereocilia bundles in all cochlear regions (e.g. open arrowheads) in Whrn^tm1Tili/Whrn^tm1Tili (whirlin-/-) mice. (C) At high magnification, the inner hair cell stereocilia appear normal (left column); the outer hair cells show patchy loss of stereocilia in the innermost (shortest) row of the hair bundle (arrowheads, middle column); the interstereocilia links of the outer hair cells appear normal (arrowheads, right column). OH, outer hair cells; IH, inner hair cells. Scale bars, 5 um (B) and 1 um (C).

Copyright

This image is from Yang J, PLoS Genet 2010;6(5):e1000955, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:160677

Associated Alleles

Symbol	Name
Whrn^tm1Tili	whirlin; targeted mutation 1, Tiansen Li

Associated Genotypes

Allelic Composition	Genetic Background
Whrn^tm1Tili/Whrn^tm1Tili	involves: 129S1/Sv * 129X1/SvJ * C57BL/6