Phenotype Image Detail

Image

Caption

Morphological defects at the basal turn of the cochlea in the Cldn9^nmf329/Cldn9^nmf329 mouse line. (A-D) Hematoxylin- and eosin-stained cross sections of cochleas from wild-type (+/+) and mutant mice (P28), at the basal turn (base) and apical turn (apex). In contrast to the intact cochlear morphology of a control mouse (A), the basal cochlear turn of a mutant mouse lacks the tunnel of Corti and contains only two rows of outer hair cells (OHCs) (B). The apical turn of the cochlea is intact in both the wild-type and mutant mice (C, D). Arrows indicate the OHCs in the mutant sample. Scale bars: 100 um.

Copyright

This image is from Nakano Y, PLoS Genet 2009 Aug;5(8):e1000610, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:152154

Associated Alleles

Symbol	Name
Cldn9^nmf329	claudin 9; neuroscience mutagenesis facility, 329

Associated Genotypes

Allelic Composition	Genetic Background
Cldn9^nmf329/Cldn9^nmf329	C57BL/6J-Cldn9^nmf329/J