Phenotype Image Detail

Image

Caption

Targeted deletion of Treml1 results in increased hemorrhage associated with inflammation. Representative macroscopic (A) and microscopic (B) views of Shwartzman lesions from wild-type (WT) and Treml1^tm1Mcvic/Treml1^tm1Mcvic (Treml1-/-) mice. Skin sections from WT and mutant mice are shown stained with H&E. Areas of hemorrhage are marked with green arrowheads. Characteristic thrombi are marked by black arrowheads. Original magnification, x40 (top panels); x200 (bottom panels).

Copyright

This image is from Washington AV, J Clin Invest 2009 Jun;119(6):1489-501 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:150578

Associated Alleles

Symbol	Name
Treml1^tm1Mcvic	triggering receptor expressed on myeloid cells-like 1; targeted mutation 1, Daniel W McVicar

Associated Genotypes

Allelic Composition	Genetic Background
Treml1^tm1Mcvic/Treml1^tm1Mcvic	C57BL/6-Treml1^tm1Mcvic