Phenotype Image Detail

Image

Caption

Sperm-egg binding assay. Light microscopy images show cumulus-free eggs from superovulated females with sperm from wild-type (+/+) (upper left panel) and no sperm from Del(8Defb1-Defb13)1Jrdo/Del(8Defb1-Defb13)1Jrdo (-/-) males bound to the eggs (upper right panel). Sperm were also incubated with 2-cell embryos as a control for non-specific binding (left egg in upper left panel). A range of 47-86 eggs per genotype were used for each set of experiments (n = 3). Original magnification x20. Graph shows comparison of the average number of sperm from wild-type and mutant males bound eggs following 45 minute incubation (mean +/- SD; n = 3). **, p<0.001.

Copyright

This image is from Zhou YS, PLoS Genet 2013 Oct;9(10):e1003826, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:204187

Associated Alleles

Symbol	Name
Del(8Defb1-Defb13)1Jrdo	deletion, Chr 8, Julia R Dorin 1

Associated Genotypes

Allelic Composition	Genetic Background
Del(8Defb1-Defb13)1Jrdo/Del(8Defb1-Defb13)1Jrdo	involves: 129P2/OlaHsd * C57BL/6N