Phenotype Image Detail

Image

Caption

(I) Histology of wild-type (WT) (Left) and Spata6^{tm1a(KOMP)Wtsi}/Spata6^{tm1a(KOMP)Wtsi} (KO) (Right) testes (Upper) and epididymides (Lower). (Scale bars: 100 um.) (J) Normal and acephalic spermatozoa in WT (Left) and mutant (Right) epididymides, respectively. Shown are phase-contrast microscopic images (Upper; scale bars: 100 um), hematoxylin and eosin-stained histology (Middle; scale bars: 10 um), and SPEM1 immunofluorescent patterns (Lower; scale bars: 10 um). Cytoplasmic droplets are indicated by white arrows (Upper) or arrowheads (Lower). Note that one or two sperm heads occasionally could be seen in the KO epididymis (Right Middle, arrowhead).

Copyright

This image is from Yuan S, Proc Natl Acad Sci U S A 2015 Feb 3;112(5):E430-9. Copyright 2015 National Academy of Sciences, U.S.A. J:217662

Associated Alleles

Symbol	Name
Spata6^tm1a(KOMP)Wtsi	spermatogenesis associated 6; targeted mutation 1a, Wellcome Trust Sanger Institute
Spata6^tm1a(KOMP)Wtsi	spermatogenesis associated 6; targeted mutation 1a, Wellcome Trust Sanger Institute

Associated Genotypes

Allelic Composition	Genetic Background
Spata6^tm1a(KOMP)Wtsi/Spata6^tm1a(KOMP)Wtsi	B6J.B6N-Spata6^tm1a(KOMP)Wtsi