Phenotype Image Detail

Image

Caption

B) Radiographic images of femora and tibiae from wild-type (WT) and Snx10^{tm1a(EUCOMM)Raba}/Snx10^{tm1a(EUCOMM)Raba} (Snx10 KD) mice show mineralization of femoral condyles in WT mice (see inset) and in mutants supplemented with calcium. (C) MicroCT analysis of femora confirms partial re-mineralization of condyles and prevention of the moth-eaten cortical bone phenotype, as a result of calcium supplementation in mutant mice.

Copyright

This image is from Ye L, PLoS Genet 2015 Mar;11(3):e1005057, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:224711

Associated Alleles

Symbol	Name
Snx10^tm1a(EUCOMM)Raba	sorting nexin 10; targeted mutation 1a, Ricardo A Battaglino

Associated Genotypes

Allelic Composition	Genetic Background
Snx10^tm1a(EUCOMM)Raba/Snx10^tm1a(EUCOMM)Raba	involves: 129S4/SvJae * C57BL/6 * C57BL/6J