Phenotype Image Detail

Image

Caption

Development of wild-type (WT), heterozygous (HET), and Cenpu^tm1Hluo/Cenpu^tm1Hluo (KO) embryos until E7.5. A. Gross morphology of WT and KO mouse embryos. E6.5 and E7.5 embryos dissected from decidua were photographed, and then genotyped by RT-qPCR. (Scale bar: 100 um). C. Histology and differentiation marker expression of embryos at E6.5. Top row: Haematoxylin and eosin staining of E6.5 embryos. Middle row: Oxt2 in situ hybridization. Bottom row: Lim1 in situ hybridization. VE: visceral endoderm; Epi: epiblast; *: detachment of the epiblast from the surrounding visceral endoderm. (Scale bar: 100 um).

Copyright

This image is from Wang X, PLoS One 2013;8(5):e63783, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:202158

Associated Alleles

Symbol	Name
Cenpu^tm1Hluo	centromere protein U; targeted mutation 1, Hongyu Luo

Associated Genotypes

Allelic Composition	Genetic Background
Cenpu^tm1Hluo/Cenpu^tm1Hluo	involves: 129S1/Sv * 129X1/SvJ * C57BL/6