Phenotype Image Detail

Image

Caption

Activated Yap1 enhances cardiac regeneration. (A) Masson's trichrome-stained heart sections of WT and Tg(Myh6-Yap1*S112A)#Eno/0 (Tg) mice at 7 days after LAD ligation performed at P28. Serial sections were cut at 500-um intervals from the site of the ligature toward the apex. (B) Quantification of fibrotic areas in heart sections displayed in A. n = 3 for WT; n = 4 for Tg. Data are mean +/- SD. **P < 0.005.

Copyright

This image is from Xin M, Proc Natl Acad Sci U S A 2013 Aug 20;110(34):13839-44. Copyright 2013 National Academy of Sciences, U.S.A. J:200670

Associated Alleles

Symbol	Name
Tg(Myh6-Yap1*S112A)#Eno	transgene insertion, Eric N Olson

Associated Genotypes

Allelic Composition	Genetic Background
Tg(Myh6-Yap1*S112A)#Eno/0	involves: C3H * C57BL/6