Phenotype Image Detail

Image

Caption

Gross appearances and histological images of the ovaries from heterozygous (Rev7^+/-) and homozygous Mad2l2^tm1Ymu/Mad2l2^tm1Ymu (Rev7^-/-) mice. Macroscopic images of the ovaries at P70 (left panels) and microscopic images of H&E-stained sections of the ovaries at P28 were shown (middle panels). Right panels are high magnification images. The ovaries are quite small and atrophic. Ovaries of adult wild-type mice at P28 have many follicles containing oocytes, whereas those of mutant females consist of stromal and epithelial cells without follicles. Scale bars, 200 um (middle panels) and 50 um (right panels).

Copyright

This image is from Watanabe N, J Biol Chem 2013 Apr 12;288(15):10459-71 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:198275

Associated Alleles

Symbol	Name
Mad2l2^tm1Ymu	MAD2 mitotic arrest deficient-like 2; targeted mutation 1, Yoshiki Murakumo

Associated Genotypes

Allelic Composition	Genetic Background
Mad2l2^tm1Ymu/Mad2l2^tm1Ymu	involves: 129 * C57BL/6J