Phenotype Image Detail

Image

Caption

Mouse colon bleeding in dextran sulfate sodium (DSS)-induced acute colitis in wild-type (WT) and Fpr2^tm1.2Jimw/Fpr2^tm1.2Jimw (mFPR2^-/-) mice. A. Anus bleeding. Mice were given 5% DSS in drinking water for 6 days. Anus bleeding was monitored daily. B. Bleeding in the colon lumen. Mouse colon was harvested at day 5 after 5% DSS intake in drinking water. The colon was paraffin-sectioned (5 um) and stained with H&E to reveal erythrocytes and leukocytes (arrows). N=9 mice per group. Scale bar = 200 um and 50 um, respectively.

Copyright

This image is from Chen K, J Clin Invest 2013 Apr 1;123(4):1694-704 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:197568

Associated Alleles

Symbol	Name
Fpr2^tm1.2Jimw	formyl peptide receptor 2; targeted mutation 1.2, Ji Ming Wang

Associated Genotypes

Allelic Composition	Genetic Background
Fpr2^tm1.2Jimw/Fpr2^tm1.2Jimw	involves: 129X1/SvJ