Gene Expression Image Detail

Reference

Figure

ID

J:125184 Yamamoto M, et al., Mech Dev. 2007 Sep-Oct;124(9-10):715-28

8

MGI:5578627

Image

Caption

(A-C) Co-detection of X-gal and Scleraxis. (A) In the trunk, somitic X-gal (blue; white arrowheads) and Scleraxis (purple-brown; red arrowheads), rib pre-cartilage (asterisks), limb (yellow arrowhead). (B and C) Hindlimb bud centro-medial portion (bracket), overlapping with Scleraxis expression (C), more lateral, distal, and proximal areas (red arrowheads). The bracket in (C) corresponds to the limits of Gig1 expression shown in (B). (D) Ventral view is shown, distal tendon rudiments (black arrowheads), developing footpads (red arrowheads), digital joints (orange arrowheads) and skin capping each of the digits (1-5). Dotted lines (E-H) correspond to the approximate position of the transverse paraffin sections shown in panels (E-H). (E) Section through digits 2-4, showing developing ventral tendons (arrowheads), dorsal tendon (arrowhead). The inset is a horizontal section of digit 3, showing the joints (orange arrowheads). (F) Section through the proximal digits showing staining of ventral and dorsal tendons (arrowheads), developing musculature (arrows), and mesenchyme and overlying ectoderm of the developing footpads (red arrowheads). (G) Section through the distal-radius/ulna. Some (black arrowhead) but not all (white arrowheads) tendon rudiments are stained at this level. An example of a tendon rudiment that is stained at this level, but not at more proximal levels (H), is marked with an asterisk. (H) In the proximal forelimb, tendon rudiments are not stained (white arrowheads). Developing muscles (black arrows) are stained. R, radius; U, ulna. In (E-H), dorsal is oriented toward the top of each panel.

Copyright

Reprinted with permission from Elsevier from 10.1016/j.mod.2007.07.002 Mech Dev 124: 715-28, Yamamoto M; Watt CD; Schmidt RJ; Kuscuoglu U; Miesfeld RL; Goldhamer DJ, Cloning and characterization of a novel MyoD enhancer-binding factor. Copyright 2007

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:5578630 (Scx) MGI:5578632 (Zfp704)
B	MGI:5578632 (Zfp704)
C	MGI:5578630 (Scx)
D	MGI:5578632 (Zfp704)
E	MGI:5578632 (Zfp704)
F	MGI:5578632 (Zfp704)
G	MGI:5578632 (Zfp704)
H	MGI:5578632 (Zfp704)
E inset	MGI:5578632 (Zfp704)