Phenotype Image Detail

Image

Caption

Spontaneous colitis in Muc2^wnn/Muc2^wnn (Winnie) mice. (D-K) HIstology of normal distal colon from a wild-type mouse (D and E) and examples of inflammation in the rectum (F-I) and distal large intestine (J and K) of untreated Muc2^wnn/Muc2^wnn mice showing leukocytic infiltration (G and I), occasional branching crypts (F and H), crypt abscesses (J and K) and focal ulcerations (I); scale bars = 20 um. Note the layer covering the mucosal surface in (F) is a granulocytic serous exudate.

Copyright

This image is from Heazlewood CK, PLoS Med 2008 Mar 4;5(3):e54, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:194148

Associated Alleles

Symbol	Name
Muc2^wnn	mucin 2; winnie

Associated Genotypes

Allelic Composition	Genetic Background
Muc2^wnn/Muc2^wnn	C57BL/6-Muc2^wnn