Phenotype Image Detail

Image

Caption

Cloning strategy for the generation of the Fcgr2b^tm1Kgcs allele. A PCR product corresponding to the promoter and three first exons from Fcgr2b from haplotype I (1, 271 bp) was first fused with the 5' homology arm (1,996 bp from haplotype III). The fusion product was then cloned into the targeting vector (pCR_LPacINeo; Ozgene). The 3' homology arm (3,905 bp from haplotype III) was then amplified and cloned in the targeting vector.

Copyright

This image is from Espeli M, J Exp Med 2012 Nov 19;209(12):2307-19, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:190890

Associated Alleles

Symbol	Name
Fcgr2b^tm1Kgcs	Fc receptor, IgG, low affinity IIb; targeted mutation 1, Kenneth G C Smith