Phenotype Image Detail

Image

Caption

Intestinal human MALT lymphomas and human-like mouse MALT lymphomas in Tg(Ly6e-MALT1)#Isg/0 (Sca1-MALT1) mice show similar histopathological pictures including typical lymphoepithelial lesions; these lymphomas expressed the pan-B cell markers CD20 or Pax5+. Magnification is 200X in figure A. (E) A typical MALT lymphoma is shown, which (e1) infiltrates lungs (e2) and salivary glands (e3), evolving into a high-grade lymphoma resembling human DLBCL involving spleen (e4), stomach (e5), kidneys (e6) and liver (e7).

Copyright

This image is from Vicente-Duenas C, Proc Natl Acad Sci U S A 2012 Jun 26;109(26):10534-9. Copyright 2012 National Academy of Sciences, U.S.A. J:185590

Associated Alleles

Symbol	Name
Tg(Ly6e-MALT1)#Isg	transgene insertion, Isidro Sanchez-Garcia

Associated Genotypes

Allelic Composition	Genetic Background
Tg(Ly6e-MALT1)#Isg/0	involves: C57BL/6 * CBA