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| Caption | Characterization of human-like mucosa-associated lymphoid tissue (MALT) lymphomas in Tg(Ly6e-MALT1)#Isg/0 (Sca1-MALT1) mice. (A) Representative hematoxylin-eosin (HE) staining analysis of the mouse lymphomas. A typical lymphoid cell population is present in the small intestine of mutant mice, infiltrating the lamina propria and the epithelium in small groups, giving rise to lymphoepithelial lesions. (B) Lymphoid tumor cells also infiltrate other tissues. (C) Lymphomas developed in the kidneys showed prominent plasma cells surrounding blood vessels, which were pleomorphic and showed occasional binuclei (marked with arrows). (D) IHC analysis of Pax5 expression in mutant lymphomas. | ||||
| Copyright | This image is from Vicente-Duenas C, Proc Natl Acad Sci U S A 2012 Jun 26;109(26):10534-9. Copyright 2012 National Academy of Sciences, U.S.A. J:185590 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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