Phenotype Image Detail

Image

Caption

Atmin^tm1.1Axbe/Atmin^tm1.1Axbe (ATMIN^delta/delta) embryos exhibit severe exencephaly. (C) Scanning electron microscopy images of wild-type (ADMIN+/+) and mutant embryos at E10.5 showing that closure of the neural tube closure is incomplete in mutant embryos. (D) At E16.5, ATMIN deficiency causes severe midbrain exencephaly and growth retardation is already noticeable.

Copyright

This image is from Kanu N, J Biol Chem 2010 Dec 3;285(49):38534-42 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:167331

Associated Alleles

Symbol	Name
Atmin^tm1.1Axbe	ATM interactor; targeted mutation 1.1, Axel Behrens

Associated Genotypes

Allelic Composition	Genetic Background
Atmin^tm1.1Axbe/Atmin^tm1.1Axbe	involves: BALB/c * C57BL/6