Phenotype Image Detail

Image

Caption

Analysis of Del(16Lipi-Usp25)1Dja/Del(16Lipi-Usp25)1Dja embryos. (B) Photos of wild-type (+/+), monosomic Del(16Lipi-Usp25)1Dja/+ (Ms1Dja/+), and nullisomic Del(16Lipi-Usp25)1Dja/Del(16Lipi-Usp25)1Dja (Ms1Dja/Ms1Dja) embryos at E10.5. Longitudinal measurements are 4 mm, 4 mm and 2.7 mm for the wild-type, monosomic and nullisomic embryos, respectively. (C) Immunohistochemical analysis using a Cleaved Caspase-3 (Asp175) antibody showed markedly increased number of apoptotic cells (brown staining; highlighted by black arrows) in the neural tube of nullisomic Del(16Lipi-Usp25)1Dja/Del(16Lipi-Usp25)1Dja E10.5 embryos. Images are representative and taken at x200 magnification.

Copyright

This image is from Migdalska AM, PLoS One 2012;7(1):e29681, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:184302

Associated Alleles

Symbol	Name
Del(16Lipi-Usp25)1Dja	deletion, Chr 16, David J Adams 1

Associated Genotypes

Allelic Composition	Genetic Background
Del(16Lipi-Usp25)1Dja/Del(16Lipi-Usp25)1Dja	involves: 129P2/OlaHsd * C57BL/6