Phenotype Image Detail

Image

Caption

Developing lymphatic circulation in Clec1b^tm1.1Ksi/Clec1b^tm1.1Ksi mice communicates with the blood circulation. A, mesenteric sections of E15.5 wild-type (CLEC-2^+/+, upper panels) and Clec1b^tm1.1Ksi/Clec1b^tm1.1Ksi (CLEC-2^-/- lower panels) embryos stained with hematoxylin and eosin (HE; left panels) and LYVE-1 (right panels). B, confocal images of intestinal cryosections of E17.5 wild-type (upper panels) and mutant (lower panels) embryos with antibodies against PECAM-1, alpha-smooth muscle actin (alpha-SMA), and LYVE-1. L, lymphatic vessels; V, vein; A, arteries. The arrows indicate blood cells.

Copyright

This image is from Suzuki-Inoue K, J Biol Chem 2010 Aug 6;285(32):24494-507 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:165898

Associated Alleles

Symbol	Name
Clec1b^tm1.1Ksi	C-type lectin domain family 1, member b; targeted mutation 1.1, Katsue Suzuki-Inoue

Associated Genotypes

Allelic Composition	Genetic Background
Clec1b^tm1.1Ksi/Clec1b^tm1.1Ksi	involves: C57BL/6