Gene Expression Image Detail

Reference

Figure

ID

J:69786 Daujat S, et al., Mech Dev. 2001 May;103(1-2):163-5

1

MGI:5444449

Image

Caption

Whole-mount in situ hybridization with (F-H) or without RNase treatment (A-E,I-J). (A,B) Lateral and frontal view of a pre-somite stage embryo at 7.5 dpc with neural groove (arrowhead). (C) Dorsal view of an 8 dpc (three to four somites) embryo. Anterior is up. (D) Lateral view of the head region of an 8-8.5 dpc (six somites) embryo. (E) Lateral view of an 8-8.5 dpc (seven somites) embryo. Arrowheads in E indicate migrating cranial neural crest cells adjacent to the hindbrain region. (F) Ventral view of an 8-8.5 dpc (eight to nine somites) embryo. (G,H) Ventral and lateral views of an 8.5 dpc (11-13 somites) embryo. The signal was conserved after RNase treatment in (F-H). (I) Lateral view of an 8.5-9 dpc (14-16 somites) embryo. Arrows in D and G-I indicate the periocular and frontonasal regions. Black arrowheads in H,I indicate neural crest-derived first branchial arch. Open arrowhead in H indicates the future second branchial arch. In I, 1,2,3 indicates the branchial arches. (J) Dorsal view of an 8.5 dpc heterozygous embryo stained first with X-Gal. The black arrowhead indicates labeled presumptive neural crest, migrating from rhombomere 4. (K) Lateral view of a control 8.5-9 dpc (12 somites) embryo hybridized with a sense probe.

Copyright

Reprinted with permission from Elsevier from 10.1016/S0925-4773(01)00339-2 Mech Dev 103: 163-5, Daujat S; Neel H; Piette J, Preferential expression of Mdm2 oncogene during the development of neural crest and its derivatives in mouse early embryogenesis. Copyright 2001

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:5444454 (Mdm2)
B	MGI:5444454 (Mdm2)
C	MGI:5444454 (Mdm2)
D	MGI:5444454 (Mdm2)
E	MGI:5444454 (Mdm2)
F	MGI:5444454 (Mdm2)
G	MGI:5444454 (Mdm2)
H	MGI:5444454 (Mdm2)
I	MGI:5444454 (Mdm2)
J	MGI:5444456 (Egr2) MGI:5444454 (Mdm2)