Phenotype Image Detail

Image

Caption

(C and D) Images of Bouin's fixed E15.5 embryos of a littermate control wild-type (Ror1^+/+;Ror2^+/+) (C) and a Ror1^tm1.2Meg/Ror1^tm1.2Meg (Ror1^-/-;Ror2^+/+) mouse with the low penetrance exencephaly phenotype (D). Ex, exencephaly.

Copyright

This image is from Ho HY, Proc Natl Acad Sci U S A 2012 Mar 13;109(11):4044-51. Copyright 2012 National Academy of Sciences, U.S.A. J:182150

Associated Alleles

Symbol	Name
Ror1^tm1.2Meg	receptor tyrosine kinase-like orphan receptor 1; targeted mutation 1.2, Michael E Greenberg

Associated Genotypes

Allelic Composition	Genetic Background
Ror1^tm1.2Meg/Ror1^tm1.2Meg	involves: 129S4/SvJae * C57BL/6 * FVB/N