Phenotype Image Detail

Image

Caption

(C) Immunofluorescence microscopy images (contrast-enhanced by conversion to grey scale and inversion of contrast) of keratin 5 filament networks in hyperosmotic shock-treated (+urea) and non-treated keratinocytes. Note more advanced network collapse in Plec^tm7.1Gwi/Plec⁺ (Ogna/+) compared to wild-type (+/+) keratinocytes. Bar, 20 um.

Copyright

This image is from Walko G, PLoS Genet 2011 Dec;7(12):e1002396, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179812

Associated Alleles

Symbol	Name
Plec^tm7.1Gwi	plectin; targeted mutation 7.1, Gerhard Wiche

Associated Genotypes

Allelic Composition	Genetic Background
Plec^tm7.1Gwi/Plec^+	involves: 129P2/OlaHsd * C57BL/6