Phenotype Image Detail

Image

Caption

c, d: Wild-type testis sections. e: Wild-type epididymis with sperm. f, g: Testis sections from confirmed Prdm9^M1045Lja/Prdm9⁺ mice exhibit complete spermatogenic block, with an absence of elongated spermatids. h: Epididymis from confirmed heterozygous mutant contains a small number of round germ cells and no sperm. i, j: Testis section from a confirmed Prdm9^M1045Lja/Prdm9^M1045Lja mutant exhibits severe germ cell loss. k: Epididymis from a homozygous mutant is devoid of germ cells.

Copyright

This image is from Weiss J, Mamm Genome 2012 Jan 19;(): and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:179895

Associated Alleles

Symbol	Name
Prdm9^M1045Lja	PR domain containing 9; mutation 1045, J Larry Jameson

Associated Genotypes

Allelic Composition	Genetic Background
Prdm9^M1045Lja/Prdm9^M1045Lja	involves: C57BL/6J * DBA
Prdm9^M1045Lja/Prdm9^+	involves: C57BL/6J * DBA