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Gene Expression Image Detail
Reference
Figure
ID
J:171409 GUDMAP Consortium, www.gudmap.org. 2004;
GUDMAP:8209
MGI:5021790
Image
Caption Image(s) contributed directly to GXD by the GUDMAP database. Zoom capability for the image(s) can be accessed via the GUDMAP link at the bottom of this page. GUDMAP provided the following information: Wnt4_Wt1_EK1_IHC260906.jpg - Nephrogenic zone. S-shaped body centre and renal vesicles; Wnt4_Wt1_EK10_IHC260906.jpg - Medulla and pelvis. Wt1 protein detected in a subset of medullary interstitium adjacent to collecting ducts. Some of these cells overlap with those that express Wnt4 RNA. The Wnt4 pattern appears to be a larger subset of interstitial cells; Wnt4_Wt1_EK2_IHC260906.jpg - Maturing and capillary loop renal corpuscles and renal vesicle at right; Wnt4_Wt1_EK3_IHC260906.jpg - Cortex & nephrogenic zone. Various nephron stages are represented. Wt1 protein in lower limb and Wnt4 RNA primarily in upper limb of comma- and S-shaped bodies; Wnt4_Wt1_EK4_IHC260906.jpg - Nephrogenic zone. S-shaped body and renal vesicles. Wt1 protein in the visceral and parietal epithelium of the proximal segment of the S-shaped body; Wnt4_Wt1_EK5_IHC260906.jpg - Nephrogenic zone. A subset of the S-shaped body at the border between the proximal and medial segments contains both Wnt4 and Wt1 positive cells. There is no expression in the distal segment; Wnt4_Wt1_EK6_IHC260906.jpg - S-shaped body connected to ureteric tip. No expression detected in the renal connecting tubule; Wnt4_Wt1_EK7_IHC260906.jpg - Nephrogenic zone; Wnt4_Wt1_EK8_IHC260906.jpg - Metanephros. Note Wt1 protein in subset of early proximal tubules and subset of cortical and medullary interstitium adjacent to collecting ducts; Wnt4_Wt1_EK9_IHC260906.jpg - Metanephroi with proximal ureter. Wt1 protein visualised with DAB in orange and Wnt4 RNA visualised with BM purple in blue.
Questions regarding this image should be directed to the GUDMAP project: gudmap-editors@gudmap.org. Information about its use in publications can be found at http://www.gudmap.org/About/Usage.html.
Associated
Assays
Label Assay & Result Details (Gene Symbol) Spatial Mapping
MGI:5540704 (Wnt4)
Other Database
Links
GUDMAP

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory