Phenotype Image Detail

Image

Caption

Phenotypic appearance of a Ppcd1/0 mouse. Enucleated eyes were fixed in 10% formalin in phosphate-buffered saline and photographed. A. Appearance of Ppcd1/0 (PPCD1) mouse, showing the enlarged anterior chamber. B. Comparison of normal (left) and mutant (right) eyes. Corneal neovasculation can be observed on the surface of the mutant cornea. The arrow indicates an anterior synechia. Age, 3 months. C. Mutant eye, showing corneal haze and cell growth across the surface of the pupil (arrow). Age, 3 months. D. Mutant eye, showing lens subluxation, corneal haze, exudate in the anterior chamber, and anterior synechia. Age, 5 months.

Copyright

This image is from Shen AL, PLoS One 2010;5(8):, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:164007

Associated Alleles

Symbol	Name
Ppcd1	posterior polymorphous corneal dystrophy 1

Associated Genotypes

Allelic Composition	Genetic Background
Ppcd1/+	involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Ppcd1/+	D2.129-Ppcd1