Phenotype Image Detail

Image

Caption

Morphological defects of the E10.5 Opa1^lilr3/Opa1^lilr3 embryo. Wild-type littermate control (a, wild type) and Opa1^lilr3/Opa1^lilr3 (lilR3, b-d) embryos at E10.5. a: Lateral view of a littermate control. b: Ventral view of mutant. Inset is a higher magnification view of the hypomorphic somites. c: Lateral view of the craniofacial and pharyngeal structures. Note the blood pooling in the frontonasal process, cranial folds, and the pharyngeal arches. d: Dorsal view of exencephaly. pa, pharyngeal arches; fn, frontonasal process; som, somites; ht, heart tube; ba, branchial arch; ov, otic vesicles. Anterior is up, posterior is down.

Copyright

This image is from Moore BA, Mamm Genome 2010 Aug;21(7-8):350-60 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:162916

Associated Alleles

Symbol	Name
Opa1^lilr3	OPA1, mitochondrial dynamin like GTPase; lilr3

Associated Genotypes

Allelic Composition	Genetic Background
Opa1^lilr3/Opa1^lilr3	involves: C3H/HeJ * C57BL/6J